Syllogisms (e.g. “All A are B; All B are C; What is true about A and C?”) are a long‐studied area of human reasoning. Riesterer, Brand, and Ragni compare a variety of models to human performance and show that not only do current models have a lot of room for improvement, but more importantly a large part of this improvement must come from examining individual differences in performance.

Die Suche nach historischen Quellen für die Leibniz’sche Philosophie scheint zunächst unerschöpflich. Durch alle in diesem Band versammelten Arbeiten wird der Einfluss der Philosophie des Aristoteles auf das Leibniz’sche Denken näher umrissen. Ein wesentliches Ziel ist es hierbei, einen Beitrag zur Analyse dieser philosophischen Beziehung zu leisten und zu zeigen, dass auch Aristoteles’ Philosophie nach Ansicht unserer Autoren entscheidend zum Verständnis des Leibniz’schen Denkens beiträgt. Die Texte befassen sich mit wesentlichen Themen der Leibniz’schen Logik und Metaphysik, z. B. mit den (...) Grundbegriffen „Monade“ (und deren „Körperhaftigkeit“), „Entelechie“, „Nous“, mit dem Problem der Individuation (Individuum, Atomismus, Einheit), mit den substanziellen Formen, mit der Wissenschaft im Allgemeinen und der Technik, mit der Transformation der Logik, mit den Prinzipien (nämlich denjenigen des zureichenden Grundes, der Individuation und der Notwendigkeit), mit Zukunft und Kontingenz sowie Vergänglichkeit, mit der Theorie der syllogistischen Folgerung, usw. Diese Themen werden stets in der Gegenüberstellung von Leibniz und Aristoteles behandelt – sie zeigen daher, wie Leibniz aristotelische Thesen übernahm, veränderte oder kritisierte. The search for the historical sources of Leibniz’s philosphy initially seems to be unending. All the essays in this volume outline more clearly the influence of Aristotle’s philosophy on Leibniz’s thought. In this context a fundamental aim is to contribute to the analysis of this philosophical relationship and to demonstrate that Aristotle’s philosophy, in the opinion of our authors, plays a decisive role in the understanding of Leibniz’s thought. The texts address fundamental themes of Leibniz’s logic and metaphysics, e.g. the basic concepts of ‘monads’ (and their ‘corporality’), ‘entelechy’ and ‘nous; the problem of individuation (individual, atomism, unity); substantial forms; knowledge in general, and technology; the transformation of logic; principles (namely those of sufficient grounds, of individuation and of necesssity); future and contingency and transientness; the theory of syllogistic deduction, etc. These themes are regularly considered in the comparison between Leibniz and Aristotle – they demonstrate how Leibniz took over, treated or criticised Aristotelian theses. (shrink)

With aims to both increase organ supply and better reflect individual donation preferences, many nations worldwide have shifted from ‘opt‐in’ to ‘opt‐out’ systems for post‐mortem organ donation (PMOD). In such countries, while a prospective donor's willingness to donate their organs/tissues for PMOD was previously ascertained—at least partially—by their having recorded positive donation preferences on an official register prior to death, this willingness is now presumed or inferred—at least partially—from their not having recorded an objection to PMOD—on an official organ donation (...) register. Using evidence regarding the presence and prevalence of selective donation preferences, and via exploration of how appeals to donation preferences are used to both motivate and legitimate shifts to opt‐out frameworks, this paper draws attention to a set of previously unexplored problems for opt‐out organ donation arising in contexts where: (a) individuals demonstrate selective post‐mortem organ/tissue donation preferences, (b) legislation provides prospective donors with the opportunity to selectively permit/refuse the donation of certain organs/tissues in line with these preferences. While selective preferences pose few problems for opt‐in systems where a selective occasion is built into the process of signing the donor register, this is not the case for opt‐out systems. The loss of this selective occasion can cause significant problems where appeals to preferences motivate/legitimate shifts to opt‐out but evidence regarding variable preferences does not feed into determinations regarding organ/tissue exclusions. The nature of these problems depends on how the authorization aspect of ‘opt‐out’ systems is framed (e.g. as presumed consent, deemed consent or, given the role of familial consent in many jurisdictions as consent in name only). (shrink)

W illia m o f Ockha m w a s a F rancisca n fria r , a theol o gia n an d a v e r y singula r philo sophe r . H e l i v e d a t a tim e o f crisi s an d durin g th e transitio n o f philosop h y an d theol o g y . Hi s secularis m i s manifeste d i n (...) th e defens e o f a radica l separatio n bet w ee n th e religious an d secula r p ow ers . Assigne d t o th e philosophica l cu r ren t o f nominalism , h e deal t a s e v ere b l o w t o th e metap h ysica l realis m o f Aristotl e an d Thoma s Aquina s an d h e ad v ocate d the separatio n o f reaso n an d f aith , bet w ee n philosop h y an d theol o g y an d thu s h e unde r mined th e ideol o gica l foundation s o f th e churc h o f hi s time . H e w a s accuse d o f heres y because o f hi s nominalism , althoug h h e himsel f condemne d P op e Joh n XXI I a s heretica l fo r his conceptio n o f p o v e r t y , a concep t f a r rem o v e d fro m ev angelica l principle s an d especial ly fro m th e notio n o f th e F rancisca n orde r . H e defende d th e separatio n o f churc h an d stat e and h e denie d th e P ope ’ s authorit y i n secula r matters . H e flat ly asse r te d freedo m o f conscience an d Luthe r too k hi m a s a teache r. (shrink)

© 2015, Springer-Verlag Berlin Heidelberg.Genetic studies have identified single nucleotide polymorphisms associated with the risk of prostate cancer. It remains unclear whether such genetic variants are associated with disease aggressiveness. The NCI-SPORE Genetics Working Group retrospectively collected clinicopathologic information and genotype data for 36 SNPs which at the time had been validated to be associated with PC risk from 25,674 cases with PC. Cases were grouped according to race, Gleason score and aggressiveness. Statistical analyses were used to compare the frequency (...) of the SNPs between different disease cohorts. After adjusting for multiple testing, only PC-risk SNP rs2735839 was significantly and inversely associated with aggressive and high-grade disease in European men. Similar associations with aggressive and high-grade disease were documented in African-American subjects. The G allele of rs2735839 was associated with disease aggressiveness even at low PSA levels in both European and African-American men. Our results provide further support that a PC-risk SNP rs2735839 near the KLK3 gene on chromosome 19q13 may be associated with aggressive and high-grade PC. Future prospectively designed, case-case GWAS are needed to identify additional SNPs associated with PC aggressiveness. (shrink)

This paper examines Gilles Deleuze’s reading of Immanuel Kant’s “Critique of the Aesthetic Power of Judgment”. We will show a) that the author holds an interpretative thesis according to which the third Kantian Critique would not be a complement but rather a foundation of the previous ones, inasmuch as the determined agreements of the first two Critiques presuppose the possibility of an indeterminate agreement between the faculties; b) that the demand for a genesis of the sensus communis by Deleuze can (...) be summed up in three requisites: discordance, contingency, and vivification; and c) in which senses Deleuze considers that the aforementioned requirements are satisfied in the Kantian text. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:NOTES AND DISCUSSIONS 69 in pre-Socratic scholarship. But he does not do justice to the religious mood which pervades the whole poem (a mood which is set by the prologue which casts the whole work into the form of some kind of religious revelation). The prologue is considerably more than a mere literary device, and the poem is more than logic. Generally, Jaeger9 and Guthrie are surely correct in (...) their judgment that any adequate interpretation of Parmenides' work (as well as that of the other early Greek thinkers) must be willing to take into account its essentially theological character and religious inspirationl~ not always grasped through strict analysis and exegesis. g Theolooy of the Early C-reekPhilosophers, trans. Edward S. Robinson (Oxford, 1947), p. lff, 90ft. agCf. Guthrie's excellent statement: "...Parmenides was at one with Heraclitus in claiming a prophetic or apocalyptic authority for his teaching." And again, the Greeks believed in "an inspiration whereby-the poet is granted deeper insight into the truth than other men" (p. 6). ED. L. MILLER University of Colorado AN UNKNOWN SEVENTEENTH-CENTURY FRENCH TRANSLATION OF SEXTUS EMPIRICUS* I. Introduction Included in a collection of manuscripts and early printed books recently acquired by the Library of the University of California, Los Angeles, from the Paris bookdealer Paul Jammes ~ are three manuscripts attributed to a certain Nicolas de la Toison, Baron de Bussy. Two of the three volumes contain extensive Latin commentaries on the major writings of Aristotle.2 The third is a miscellaneous volume written in three different hands, which contains, among other things, a complete French translation of the extant writings of Sextus Empiricus (c. A.D. 160-210).3 I * I would like to express my thanks to Mr. Richard O'Brien, Western European Bibliographer of the UCLA Library, for his help in numerous ways, who made it possible for me to consult this material during my sojourn in Los Angeles, even before it had been officially catalogued by the Library. I would also like to thank Professors Donald Kalish and Robert Yost of the UCLA Department of Philosophy for their support in making it possible for the collection to be purchased. 1For a brief description of the collection as a whole see Charles B. Schmitt, "Acquisition of Early French Books and Manuscripts", UCLA Librarian, XIX (1966)~25. 2These two manuscripts are bound m red leather with gold tooling. Thear present shelf mark is Collection 968, Box 2. On the spines is written: (1) PHILOSOPHIA.TO.I, and (2) METAPHYSIC ET PHYSICA TO.2. They measure approximately 10 X 14 cm. and each contains about 600fois. At the beginning of Vol. I, in a later hand (19th century?), we read: "Nicolas de la Thoison, baron de Bussy, qui 6crivit ces m6moires, 6tait conseiller laic au Parlement de Bourgogne. Il fur pourru par la r6signation de Pierre Catherine le IV Ddcembre M.DC.XLV et regu le XXIX janvier M.DC.XLVI. I1portait: de queueles dune bands d'or charges en coeur d'une quints feuiUe d'azur--ainsi qu'on le volt dans le Parlement de Bourgogne [Dijon, 1649]de Pierre PaiUot, p. 326." There is also a drawing of the coat-of-arms which has been described. That the de la Toison coat-of-arms is a quintefeuille is verified by Theodore de Renesse, Dictionnaire des figures h$raldiques (Brussels, 1894-1903) III, 461. The passage cited above from the manuscript is directly quoted from Pierre Paillot, Le Parlement de Bouroongne [I], son origins, son $tablissemerit, et son progr~s (Dijon, 1649), p. 326. s A description of this manuscript will be found in the Appendix. 70 HISTORY OF PHILOSOPHY shall here only give a preliminary survey of this third manuscript, pointing out some of the more interesting features and mentioning some problems connected with it which should be investigated further in more detail. As is now well-known the writings of Sextus Empiricus, which form the major extant compendium of ancient skeptical philosophy, had quite a significant impact on sixteenth and seventeenth-eentury thought, after their reintroduction in the sixteenth century. ~ Sextus' works were available in printed Latin editions after 15695 and the Greek text was printed in... (shrink)

"It is the purpose of this article to attempt to re-examine the account of Thrasymachus' doctrine in Plato's Republic, and to show how it can form a self-consistent whole. [...] In this paper it is maintained that Thrasymachus is holding a form of [natural right]." Note: Volume 40 = new series 9.

This book offers an introduction to the Sophists of fifth-century Athens and a new overall interpretation of their thought. Since Plato first animadverted on their activities, the Sophists have commonly been presented as little better than intellectual mountebanks - a picture which Professor Kerferd forcefully challenges here. Interpreting the evidence with care, he shows them to have been part of an exciting and historically crucial intellectual movement. At the centre of their teaching was a form of relativism, most famously expressed (...) by Protagoras as 'Man is the measure of all things', and which they developed in a wide range of views - on knowledge and argument, virtue, government, society, and the gods. On all these subjects the Sophists did far more than simply provoke Plato to thought. Their contributions were substantial and serious; they inaugurated the debate on many central philosophical questions and decisively shifted the focus of philosophical attention from the cosmos to man. (shrink)

In this paper, the author attempts to explore some of the problems connected with the formulation and application of international biomedical ethical guidelines, with particular reference to Africa. Recent attempts at revising and updating some international medical ethical guidelines have been bedevilled by intractable controversies and wrangling regarding both the content and formulation. From the vantage position of relative familiarity with both African and Western contexts, and the privilege of having been involved in the revision and updating of one of (...) the international ethical guidelines, the author reflects broadly on these issues and attempts prescribing an approach from both the theoretical and practical angles liable to mitigate, if not completely eliminate, some of the problems and difficulties. (shrink)

Professor W. B. Anderson'S paper ‘Livy and the Lexica’ in C.Q. XXV., 1931, pp. 38–48, prompts me to put together from my notes this further list of words and idioms used by Livy but not recorded in the lexica as Livian. With one or two clearly indicated exceptions, I have included nothing which is given in Lewis and Short, Forcellini-Corradini-Perin or Georges, and I have included nothing in which Mr. Anderson has anticipated me, except that in a few places I (...) have added to the citations he gives; but my citations make no more claim to be exhaustive than his do. I have given within parentheses the authors who are cited by the lexica for a particular word or use, but I have refrained from adding other authorities. (shrink)

F.A.Hayek is generally considered to be a representative of what, in regard to the methodology of the human sciences, is commonly referred to as ?methodological individualism?; (MI). This paper is an attempt to determine the exact nature and significance of Hayek's own particular brand of ?individualism.?; In particular, it attempts to show that Hayek's MI is grossly misinterpreted when it is viewed as being merely another instance of the atomistic or analytic individualism characteristic of much modern thinking. The ?true?; individualism (...) that Hayek argues for is in fact one which highlights the irremediably social nature of human being that recent hermeneutical and postmodern writers have stressed. (shrink)

Professor W. B. Anderson'S paper ‘Livy and the Lexica’ in C.Q. XXV., 1931, pp. 38–48, prompts me to put together from my notes this further list of words and idioms used by Livy but not recorded in the lexica as Livian. With one or two clearly indicated exceptions, I have included nothing which is given in Lewis and Short, Forcellini-Corradini-Perin or Georges, and I have included nothing in which Mr. Anderson has anticipated me, except that in a few places I (...) have added to the citations he gives; but my citations make no more claim to be exhaustive than his do. I have given within parentheses the authors who are cited by the lexica for a particular word or use, but I have refrained from adding other authorities. (shrink)